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Monitor Closely (three)pentobarbital will lower the level or outcome of diazepam intranasal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Sturdy or average CYP3A4 inducers could maximize price of diazepam elimination; thus, efficacy of diazepam could be reduced.pentobarbital will lessen the level or influence of ari